Increased ALKP in dogs what's next
Course Description
ALP activity is commonly used as a marker for hepatic disease in canines. However, ALP is a group of enzymes, and increased levels can indicate various conditions. In dogs, there are two isoenzymes: intestinal (including Corticosteroid-induced ALP “C-ALP” and Intestinal ALP “I-ALP”) and tissue non-specific (including Liver ALP “L-ALP”,Bone ALP “B-ALP”,Placental ALP “P-ALP”, and Kidney ALP “K-ALP”). The total ALP activity reflects C-ALP, L-ALP, and B-ALP combined. This lecture will define the complexity of the diagnostic algorithm of raised ALP activity in dogs and will elaborate on the causes for accurate interpretation and diagnosis. Demystify the path of ALP activity in dogs!
Course Content
- Introduction about ALP activity and the 2 isoenzymes of ALP
- Liver ALP -Corticosteroid-induced ALP
- Bone ALP
- Other ALP increases
- Determination of isoforms
- Approach to dogs with raised ALP
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Course Content
Emma Hooijberg
BVSc PhD CertGP(SAP) DipECVCP, Associate Professor and Head of Section of Clinical Pathology, Dept. of Companion Animal Clinical Studies at the Faculty of Veterinary Science, University of Pretoria
Summary of activities and interests
- Graduated from Faculty of Veterinary Science, University of Pretoria, South Africa with a BVSc in 2001.
- Spent 6 years in small animal practice in the UK.
- Completed a residency in Veterinary Clinical Pathology in Vienna, Austria, and became a Diplomate of the European College of Veterinary Clinical Pathology in 2012.
- Worked in academia and a commercial diagnostic lab in Vienna for a further 2 years.
- Joined the Dept. of Companion Animal Clinical Studies at the Faculty of Veterinary Science, University of Pretoria at the end of 2014.
- Completed PhD investigating various aspects of clinical pathology in the white rhinoceros in 2018.
- Currently Associate Professor and Head of Section of Clinical Pathology.
- Involved in management and diagnostic service in the lab, undergraduate and postgraduate teaching and research.
- Past post-graduate students: 2 ECVCP residents, 3 Masters-level students, 1 PhD student.
- Current post-graduate students: 3 Masters-level students, 3 PhD students.
- 38 publications: ORCID: 0000-0002-4367-799X.